Within the past 1 753 days beginning January 28, 2021, plos.org's accessibility has been checked 19 times. Responding with a code 200 in its latest recorded uptime on November 10, 2025, plos.org showcased functionality 19 times across all conducted checks. No instances of plos.org being down occurred during the inspections that were conducted as of November 16, 2025. Based on the replies, there were no indications of errors in any of the responses as of November 16, 2025. A response from plos.org was recorded at 0.252 seconds on November 10, 2025, differing from 0.405 seconds on average.